Phoslo (Calcium Acetate)
By Linda Schoch and Riley Friedl
Who: People who suffer from end stage renal disease get this drug
What: This drug is classified as a mineral and electrolyte replacement supplement, it works by binding to phosphate in the body, with forms a insoluble calcium phosphate complex this helps to facilitate excretion. Pharmacokinetics: absorbed through GI and it requires vit D to be used in the body, it spreads through body and can be found in breast milk and placenta, it is excreted in the feces (largest %) and the rest through the urine.
When: Dosing is 1334 mg with/before each meal
Where: This drug is given in the hospital and patients can also take it at home as well as long as they are monitoring for symptoms of hypercalcemia.
Why: this drug controls hyperphosphatemia due to the fact that ESRD patients tend to have high levels of P
How: it is given PO, with or before meals, and it is important to monitor the serum Ca and P levels, if the patient is on digoxin then monitor for s/s of toxicity. The most common side effects include: constipation, arrhythmia, bradycardia, nausea, vomiting, and renal calci.